Kidney & Heart, study & practice

Kidney & Heart, study & practice

Index

Chatbot NDT-GPT¶AI  Nephrology Dialysis Transplantation (CORPUS-NDT) 

CORPUS-NDT
CORPUS-NDT

CORPUS-NDT includes six corpuses on Glomerulonephritis (GN) , Diabetic Nephropathy (DN) , Chronic Kidney Disease (CKD) , Acute Kidney Injury/Disease (AKI/D) , Endstage Renal Disease Renal Replacement Therapy (ESRD~RRT) & Transplant Kidney (TK) 

CORPUS-NDT is a compilation of knowledge and references of Nephrology Dialysis and Transplant. The links are done with AI. It consists of the following corpuses of major divisions of NDT. 

  1. CORPUS GN
  2. CORPUS DN
  3. CORPUS HTN
  4. CORPUS CKD
  5. CORPUS AKI AKD 
  6. CORPUS FEAB
  7. CORPUS ESRD RRT 
  8. CORPUS TK

CORPUS NDT CHATBOT-GPT

=========================

Compiled by AI

___________________________

@ CORPUS-GN 

@ CORPUS-DN

@ CORPUS-HTN

@ CORPUS-CKD~DMCH

@ CORPUS-AKI/AKD

@ CORPUS-FEAB

@ CORPUS-ESRD/RRT 

@ CORPUS-TK

(Compiled by AI)

____________________________


1. CORPUS-GN

Glomerulonephritis

Chatbot GN-GPT¶AI


1. Studies and Trials on GN

Section A   Trials
> Point 5 - (ANCA)
> Point 8c - (LN)
> Point 9 - (GN)
 

Section B   Critical appraisals
> Point 1 - (LN)
> Point 3 - (ANCA)
> Point 5 - (GN)
 


2. Guidelines and Protocols in GN 

> Point 1 - (KDIGO-GN)
> Point 3 - (PPE)
> Point 4 - (RPGN)
> Point 10 - (RBX)


3. Immunology and Immunotherapy in GN

¶ Part (i)  Lymphocyte, origin, migration & distribution 

¶¶ Part (ii) - Activities related to immunology
Section A Immunology of native kidney
> Point 1- Types of immuno-therapy
> Point 2- Immunoglobulin
> Point 3- Polyclonal
> Point 4- Orthoclonal
> Point 5- Monoclonal **
> Point 6- Small molecules
> Point 7- CAR-T Immuno-therapy
> Point 8- Puzzle game in the cartoon
** (Immune check point inhibitors under Monoclonal Point) 

Section B: Immunological management of Glomerulonephritis
> Point 1- Induction therapy for remission
> Point 2- Maintenance therapy for remission
> Point 3- Adjuvant therapy
> Point 4- Prophylaxis
> Point 5- Treatment of Relapse cases



4. Immunology and Immunotherapy in ANCA associated GN

> Point 1- Classification of vasculitis
> Point 1- Nutshell
> Point 2- Atlas of vasculitis
> Point 3- Other vasculitis
> Point 4- Pathophysiology
> Point 5- Aetiologic factors
> Point 6- Management
> Point 7- Investigations
> Point 8- Disease specific management
 



5. Presentations on GN 

Section A
> Point 4- (GN)
> Point 14- (LN) 

Section B
> Point 12- (FSGS)
> Point 13- (GN)                                                 

> Point 14- (Haematuria)
> Point 29- (PSGN)
> Point 30- (Pregnancy)
> Point 33- (RBX)
> Point 41- (Viral G)

Section C
> Point 1- (IgA-Nephropathy)
 


6. Journal Papers 

Section A Internal medicine papers
> Point 2- (Amyloidosis)
> Point 20- (Lymphocyte)
> Point 22- (MGRS)
> Point 23- (Nephrotic Syndrome)
> Point 25- (Sarcoidosis) 

Section C  AJKD
> Point 3- (ANCA)
> Point 8- (Renal biopsy)
> Point 12- (Pregnancy)

Section D - eBook
> Point 2- (Clin Nephrology, Woo KT)
> Point 3- (Clin Nephrology, Dustry)
> Point 13- (Nephrotic Syndrome)

=========================


2. CORPUS DN

Diabetic Nephropathy

Chatbot DN-GPT¶AI



1a. Studies and Trials on DN

Section A - Trials
> Point 10- (DN)
> Point 11- (ALTITUDE study)

Section B - Critical appraisals
> Point 9- (DN)
 


1b. Studies and Trials on SGLT2I    

Section C
> Point 4- (SGLT2I studies)


2. Guidelines and Protocols in DN
> Point 1- (KDIGO DN & ADA 2023)


3. Diabetic micro and macro vasculopathy

Section A
> Point 17- Diabetic micro and macro vasculopathy


4. DN therapy in CKD

Section B
> Point 2- (Diabetic control)
> Point 3- (New agents)


5. Presentations on DN

Section B
> Point 1- (DN studies comparison)
> Point 11- (DN)

Section C
> Point 4- (Cardio-Diabetic forum)


6. Journal Papers

Section A-_Internal medicine papers
> Point 17- (DM Pathology forum)

Section C- AJKD)
> Point 12- (Pregnancy related)
> Point 15- (DN)

Section D- eBook
> Point 2- (Clin Nephrology, Woo KT)
> Point 3- (Clin Nephrology, Dustry)



==========================

3. CORPUS-HTN

Hypertension 

Chatbot HTN-GPT¶AI


1. Studies and Trials on HTN

Section A [Part 11] Trials

> Point 1 - (AASK trial)
> Point 2 - (ABCD (absolute blood pressure control) trial)
> Point 3 - (ACCORD. (Action to Control Cardiovascular Risk in Diabetes))
> Point 4 - (Framingham heart study)
> Point 5 - (ON-TARGET study) 

> Point 6 - (  ALTITUDE study on Aliskerin)
> Point 7 - (Aliskerin, AVOID, ALTITUDE, APOLLO, ATMOSPHERE studies)
> Point 8 - (SPRINT trial)
> Point 9 - (RCT on Spironolactone PATHWAY-2)
> Point 10 - (Symplicity HTN-2 trial, sympathetic denervation.)


2. Guidelines and Protocols in HTN 

¶ Part 8 (Hypertension) 

> Point 1 - (JNC8 Hypertension guideline)
> Point 2 - (ESH & ESC NEW GUIDELINES
> Point 3 - (KDIGO BP GUIDE 2023
> Point 10 - (Hypertension - Risk Factors Prevention )


3. Genesis HTN 

¶ Part (i)- 

Section A 

> Point 25- Renal Physiology, Prostaglandin,
> Point 22- Metabolic syndrome
> Point 20- Hypertension pathophysiology   

¶¶ Part (ii) -
> Point 1- RAS
> Point 2- Malignant HTN
> Point 3- Hypertensive heart disease
> Point 4-  Hypertension in CKD 



4. Pathophysiology of HTN 

> Point 1- Hypertension pathophysiology 
> Point 2-  Hypertension in pictures  

  

5. Presentations on HTN 

Section A
> Point 5- (Hypertension in pictures )

Section B
> Point 12- (Cardiorenal syndrome)
> Point 13- ( Intradialytic Hypertension by Prof Gawad,)


6. Journal Papers on HTN

Section A Internal medicine papers
> Point 24- Renal Physiology, Prostaglandin, NSAID

Section D - eBook
> Point 2- (Clin Nephrology, Woo KT)
> Point 3- (Clin Nephrology, Dustry)


=====================================

4. CORPUS CKD

Chatbot CKD-GPT ¶AI

(Chronic Kidney Disease - Diagnosis Management Counsel & Help) Chatbot CKD-GPT¶AI


1. Studies and Trials on CKD

In Community

Section C
> Point 2- (Community study)


In Clinic

Section A- Trials
> Point 6- (Anemia)
> Point 10- (CKD-DN)
> Point 11- (Hypertension)
> Point 15- (Gout, MBD)
Section B - Critical appraisals
> Point 6- (CKD)
> Point 7- (Anemia)
> Point 9- (DN)
> Point 10- (MBD)


2. Guidelines and Protocols in CKD 

> Point 1- (CKD Diagnosis & Evaluation)
> Point 4- (GN, MBD, ADPKD, Immunisation)
> Point 5- (Diet)
> Point 8- (Hypertension)


3. Diagnosis, evaluation, management in CKD

In Community 

> Point 1 - Community-based Kidney Medicine - basic education
> Point 2 - CKD Education at Community - risks for development of CKD
> Point 3 -  Preventive Nephrology - once you develop CKD, what do you need to do to prevent progression
> Point 4 - How To Select CKD Friendly Food
> Point 5 - Pandemic and CKD
> Point 6 - How-to-lower-creatinine-levels-fast
> Point 8 -  References:
CKD MANUAL
CKD Initiative Poster
CKD Management Logistics
CKD Primary Care Presentation
CKD Initiative vocal presentation
 

In Clinic

Section C
> Point 2- (A2ZofCKD)
Section B
> Point 2- (4, 5, 6 (CKD)
Section A
> Point 8- (Investigstions)


4. Renoprotection and metabolic management in CKD

Section A - CKD Medicines
Section B - Reno protective medicines
Section C - Dietary and other non-drug advices


5. Presentations on CKD

Section A- Presentation for students
> Point 4- (Glomerulonephritis)
> Point 5- (Hypertensioninpictures)
> Point 8- (Renal investigations)
> Point 9&10- (Renal stone disease &  Images)
> Point 11- (Tubular transport)
> Point 13- (VUR)
> Point 14- (Lupus nephritis)

Section B- Presentations for residents
> Point 4- (CKD complication and outpatient management)
> Point 5- (CKD - taking care of patients)
> Point 6- (CKD/AKD biomarker))
> Point 9- (Cyst in kidney & tubular disorders).Gout and CKD)
> Point 10- (Contrast associated nephropathy)
> Point 11- (Diabetic nephropathy)
> Point 12- (FSGS)
> Point 13- (GN- Importance of Non-immune rx and immune rx) >Point 14- (Gout, uric acid and CKD)
> Point 24- (Hyperphosphatemia- non-renal)
> Point 25- (Interstitial nephritis- CIN)
> Point 26- (Interstitial nephritis -AIN)
> Point 27- (Oxalate nephropathy)
>  Point 34- (Renal Bone disease)
> Point 42- (Renal Stone Disease) 

Section C- Presentation for the Faculty
> Point 2- (A2Z4CKC (A to Z for Community Kidney Care)
> Point 4- (Asian Cardio Diabetic Forum by PACE-CME - Saving kidney & saving heart in diabetes, new horizon)
> Point 6- (Oxalate in food and kidney, pear Review Lecture)


6. Journal Papers on CKD

Section A- Internal medicine papers
> Point 8- (Chinese herb nephropathy)
> Point 19- (eGFR review)
> Point 21- (Metabolic syndrome)
> Point 24- (Ckd & NSAID) 

Section C- AJKD papers
> Point 1- (CAN)
> Point 14- (hypertension in CKD)
> Point 20- (Anemia in CKD)
> Point 22- (Fluid balance)

Section D- eBook
> Point 2- (Clin Nephrology, Woo KT)
> Point 3- (Clin Nephrology, Dustry)


7. Counsel and Help

> Point 1 - How to KNOW the Kidney is at risk    

> Point 2- How do you PREVENT CKD   

> Point 3 - How do you HALT CKD    

> Point 4 - How do you RETARD CKD 

> Point 5 - How do you TREAT CKD    

> Point 6 - How do you pick FOOD in CKD 

> Point 7 - How do you PLAN for CKD     



==========================


5. CORPUS AKI/AKD

Acute Kidney Injury/Disease   

Chatbot AKI/AKD-GPT¶AI



1. Studies and Trials on AKI

Section A - Trials
> Point 2 - (AKI Trials)
> Point 4 - (AJKD summary Table on different AKI Trials)
> Point 4 - (Cardiorenal syndrome Trials)
> Point 7 - (Hyperkalemia Trials)
Section B - Critical appraisals
> Point 4- (AKI)

Non AKI, ICU Trials
Section A
> Point 3- (BALANCE & SALT-ED Trials)


2. Guidelines and Protocols in AKI  

> Point 2 - (KDIGO AKI)
> Point 3 - (Plasmapheresis)


3. AKI/D aetio-pathology review   

Section A - AKI
> Point 1- What AKI does
> Point 2- How AKI happens
> Point 3- AKI classification
> Point 4- What will you do
> Point 5- Management
> Point 6- Clinical types of AKI
> Point 7- Pathophysiology and Morphological changes
> Point 8- CRRT in AKI
> Point 9- Fluid resuscitaion

Section B - AKD
> Point 1- Pathogenesis
> Point 2- Maintenance phase
> Point 3- Worsening phase
> Point 4- Recovery phase
> Point 5- Assessment of AKD (Glomerular & Tubular assessment, Urinary proteomics, Segmental biomarkers, Renal biopsy)
> Point 6- Management and precautions, Drug dosing, Monitoring)



4. Fluid Electrolytes Acid-base Balance (FEAB)

Section A - Fluid
Section B - Electrolytes
Section C - Acid-base

Section A - Fluid balance
> Point 1- Water supply
> Point 2- Hypernatraemia
> Point 3- Getting water
> Point 4- Osmolar gap

Section B - Hyponatremia
> Point 1- Getting sodium, Sodium preparations, Potassium preparations and Other means
> Point 2- Clinical categories, Clinical approach, Laboratory tests, Sodium replacement
> Point 3- Sodium replacement

Section C - Acid-base balance
> Point 1- Acid-base balance
> Point 2- Compensation
> Point 3- Anion gap
> Point 4- Delta ratio
> Point 5- Urinary anion gap
> Point 6- Lactic acidosis
> Point 7- Management of metabolic acidosis
> Point 8- Metabolic alkalosis
> Point 9- Hypokalaemia and
hyperkalemia


5. Continuous Renal Replacement (CRRT) For the AKI in critically ill patients
(Critical Care Nephrology - CCN)

> Point 1- Indications
> Point 2- Modalities
> Point 3- Differences among modalities
> Point 4- Principles
> Point 5- Consumables
> Point 6- Replacement fluids
> Point 7- prescriptions
> Point 8- Other blood purification methods


6. London AKI Network         

> AKI STRATEGY DOCUMENTS

> AKI COMP

> AKI OBSTETRIC PATHWAY 

> AKI CARE BUNDLE

> CARE BUNDLE CHK LIST

> CIN

> FEAB

> PERIOPERATIVE CARE 

> REFERRAL FROM PHC

> REFERRAL TO DKD CHECK LIST 

> REFERRAL FROM WARD

> RISK PREVENTION & RECOGNITION 

> STOP AKI CHK LIST

> TEACHING MATERIALS.

> TRANSFER FROM ICU TO DKD

> REFERRAL FROM WARD CHECK LIST   

                                           

7. Presentations papers

Section A
> Point 1- (AKI)
> Point 12- (Sepsis)

Section B
> Point 7- (CES)
> Point 8- (CRS)
> Point 10- (CIAKI)
> Point 16- (Hepatorenal syndrome)
> Point 17- (Hemolytic uremic syndrome)
> Point 18- (Hemophagocytic syndrome)
> Point 22- (Poisoning)


8. Journal Papers   

Section A- (Internal medicine papers) -  26 (Septic shock, NEJM)

Section C-  (AJKD)
> Point 1- (CIAKI)
> Point 2- (CCN)
> Point 6- (hyperkalemia)
> Point 11- (AKI)
> Point 18- (AKI Core curriculum)
> Point 21- (Fluid balance)

Section D   eBook
> Point 2- (Clin Nephrology, Woo KT)
> Point 3- (Clin Nephrology, Dustry)



=======================

6. CORPUS FEAB

Fluid Electrolytes Acid-base.

Chatbot FEAB-GPT¶AI

[14/04/2023]


1. Studies and Trials on FEAB

Section A - Trials
> Point 2 - (AKI Trials)
> Point 4 - (AJKD summary Table on different AKI Trials)
> Point 7 - (Hyperkalemia Trials)
Section B - Critical appraisals
> Point 4- (AKI)

ICU Trials
Section A
> Point 3- (BALANCE & SALT-ED Trials)


2. Guidelines and Protocols in FEAB 

> Point 2 - (KDIGO AKI)
> Point 3 - (Hyperkalemia UK)


3. Fluid Electrolytes Acid-base Balance [CORE POINTS]

Section A - Fluid
Section B - Electrolytes
Section C - Acid-base

Section A - Fluid balance
> Point 1- Water supply
> Point 2- Hypernatraemia
> Point 3- Getting water
> Point 4- Osmolar gap

Section B - Hyponatremia
> Point 1- Getting sodium, Sodium preparations, Potassium preparations and Other means
> Point 2- Clinical categories, Clinical approach, Laboratory tests, Sodium replacement
> Point 3- Sodium replacement

Section C - Acid-base balance
> Point 1- Acid-base balance
> Point 2- Compensation
> Point 3- Anion gap
> Point 4- Delta ratio
> Point 5- Urinary anion gap
> Point 6- Lactic acidosis
> Point 7- Management of metabolic acidosis
> Point 8- Metabolic alkalosis
> Point 9- Hypokalaemia and
hyperkalemia


4. FEAB aetio-pathology review  in AKI/AKD

Section A - AKI
> Point 9- Fluid resuscitaion
Section B - AKD
> Point 4- Recovery phase


5. Continuous Renal Replacement (CRRT) - FEAB
> Point 6- Replacement fluids
> Point 7- prescriptions


6. London AKI Network - 

> Point- FEAB FLUID   

> Point- Electrolytes            

                                              

7. Presentations papers

Section B
> Point 22- (Hypernatraemia)                              > Point 23- (Hyponatremia)
> Point 32 - (Metabolic alkalosis) 


8. Journal Papers 

Section C- 
> Point 4 - (2020 hyponatraemia hypernatraemia core curriculum)
> Point 6- (hyperkalemia)
> Point 21- (Fluid balance)

Section D   eBook
> Point 2- (Clin Nephrology, Woo KT)
> Point 3- (Clin Nephrology, Dustry)

======================

======================


7. CORPUS- ESRD&RRT

(Endstage Renal Disease & Renal Replacement Therapy)

Chatbot ESRD~RRT-GPT¶AI


1. Studies and Trials on ESRD/RRT

Section A
> Point 6- Anemia in ESRF Trials
> Point 11-  Hypertension Trials
> Point 12- Peritoneal dialysis Trials
> Point 13- Gout and MBD Trials
Section B (Critical appraisals)
> Point 7- Anemia
> Point 11- Hemodialysis
> Point 12- Peritoneal dialysis


2. Guidelines and Protocols ESRD/RRT ,
> Point 6- KDIGO Haemodialysis
> Point 8-  Hypertension
> Point 9- Peritoneal dialysis
> Point 13- Gout and MBD Trials


3.ESRD-etiopathology   

Part A- ESRD
Section A
> Point 2- Pathophysiology and Morphological changes, Menifestation),
> Point 5- Hypertension
> Point 13- VUR
Section B
> Point 14- Gout and CKD
> Point 34- Renal Bone Disease
> Point 36- Sepsis in ESRD

Part B- Medicines used in ESRD

Section A: Medicines used for
> Point 1- Anaemia management
> Point 2- Phosphate binders
> Point 3- PTH suppression
> Point 4- Mineral Bone disease
> Point 5- Medical parathyroidectomy
Calcimimetic, cinacalcet in tertiary HPTH
> Point 6- Etelcalcetide in secondary HPTH
> Point 7- TPDI & Post TPDI protocol

Part C- RRT in ESRD

> Point 1- Renal replacement therapy introduction
> Point 6- Medicines used in ESRF during dialysis


4. RRT (Renal Replacement Therapy

Part A- Haemodialysis
> Point 2- Vascular access
> Point 3- Complications
> Point 4- Dialyser
> Point 5- Dialysis prescription
 

Part B- Peritoneal Dialysis
>Point 7- Peritoneal dialysis


5. Presentations papers

> Point 14- Haemodialysis Technique Adequacy
> Point 20- Intradialytic hypotension IDH
> Point 21- Intradialytic Hypertension
> Point 31- Haemodialysis for Nurses
> Point 8-  Vascular access Catheters


6. Journal Papers

Section A
> Point 26- Septic Shock (NEJM)

Section C- (AJKD)
> Point 6- Potassium
> Point 20- Anemia
> Point 22- Dialysis
> Point 23- HD core curriculum
> Point 24- Renal bone disease
> Point 21- Fluid balance 

Section D- (eBook)
> Point 2- (Clin Nephrology, Woo KT)
> Point 3- (Clin Nephrology, Dustry)
> Point 5- (Drug Dialysis)
> Point 12- (Classic review - Renal Replacement Therapy).

==========================

==========================


8. CORPUS TK

(Transplant Kidney)

Chatbot TK-GPT¶AI



1. Studies and Trials on Renal Transplant 

> Section A- 14 (Renal Transplant Trials)

> Section B- (Critical appraisals) 13 (Transplant Kidney). 


2. Guidelines and Protocols TK

> Point 4- KDIGO Vaccination
> Point 12- Transplant Donor Recipient
> Point 9- Peritoneal dialysis


3. GRAFT Acceptance and Rejection review  

Part i- Lymphocytes
Lymphocyte, origin, migration & distribution. 

Part ii- Immunology in transplant

Section A- Activities related to Transplant Immunology:
> Point 1- Immunology of transplant
> Point 2-Types of immuno-therapy.
> Point 3- Immunoglobulin
> Point 4- Polyclonal,
> Point 5- Orthoclonal,
> Point 6- Monoclonal*
> Point 7- Small molecules
> Point 8- CAR-T Immuno-therapy
>Point 9- Puzzle game in the cartoon
* (Immune check point inhibitors under Monoclonal section) 


4. Transplant Donor

Part A- Donor types
> Point 1- Donor classification
> Point 2- DBD
> Point 3- DCD
> Point 4- Maastricht classification
> Point 5- Prognosis
> Point 6- Living donor

Part B- Donor recipient matching
> Point 7- Tissue typing and Crossmatch 

Part C- Donor and Recipient selection
> Point 3- Donor recipient selection

Part D- Donor based graft outcome
> Point 8- Graft function and survival
> Point 9- Issues facing transplant


5. Transplant Recipient

Part A- Recipients immune identity
> Point 1- Short history of transplant
> Point 2- Transplant immunology

Part B- Recipient immunology
> Point 3- Donor & Recipients selection
> Point 4- Mechanism of graft rejection
> Point 5- Mechanism of T-cell upregulation

Part C- Transplant Immunotherapy
> Point 6- Immunosuppressives
> Point 7- Basic principles of Immunosuppressive regime and protocol flowsheet

Part D- Complications Transplant related
> Point 8- Post-transplant complications
> Point 9- Overview of graft rejections
> Point 10- Revised BANFF classification
> Point 11- Chronic graft rejections
> Point 12- Non immune complications


6. Pathophysiology of Immunosuppression and Tolerance

> Point 1- Cellular and humoral mechanism
> Point 2- Transplant tolerance
> Point 3- Complete tolerance - congenital, acquired
> Point 4- Prope tolerance
> Point 5- CAR-T therapy for tolerance 


7. References and TK Immunosuppressive Protocols 

> Point 6- References
> Point 7- TK TRANSPLANT Protocols 


8. Presentations papers

Section A > Point 2 (Renal Transplant)
Section C > Point 5 (Issues facing transplant in next decade)


9. Journal Papers 


Section A (Internal medicine papers)
> Point 4- (Basic Genetics),
> Point 5- (Basic and Formal Genetics),
> Point 6- (Basic Histocompatibility Test),
> Point 20- (Lymphocyte origin, migration and distribution),
> Point 28- (Tolerance in. Transplant)
> Point 29- (Transplant Pathology),
> Point 30- (Tolerance Protocols for Developing Countries),
> Point 31- (Urinary Proteomics in Transplant).

Section C (AJKD)
> Point 5- (Transplant Rejection Atlas),                                                > Point 9- (Transplant Biopsy),
> Point 16- (Management of Transplant by GP),
> Point 17- (Recipient Management),
> Point 19- (Donor Management).


Section D (eBook)
> Point 2- (Clin Nephrology, Woo KT),
> Point 3- (Clin Nephrology, Dustry),
> Point 6- (Transplant Kidney, eBook). 

=========================

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